Biogerontology

Biogerontology is the interdisciplinary scientific study of the biological processes of aging, its causes, and potential interventions to extend lifespan and healthspan. It combines biology, medicine, and gerontology to explore the mechanisms behind age-related decline at the molecular, cellular, and organismal levels. Researchers investigate genetic, environmental, and lifestyle factors contributing to aging, and seek methods to mitigate age-related diseases and improve overall quality of life in older adults.

Biogerontology meaning with examples

• Researchers in biogerontology are actively investigating senolytics, drugs that selectively eliminate senescent cells, to combat age-related diseases. Studies explore the impact of calorie restriction and intermittent fasting on lifespan extension. Furthermore, understanding epigenetic changes associated with aging is a major focus.
• The field of biogerontology examines the role of telomeres and DNA damage in cellular aging. Studies assess the efficacy of antioxidants and other interventions to slow oxidative stress. Scientists explore how aging affects the immune system, with the goal of promoting healthier aging and reducing age-related vulnerability.
• Understanding the mechanisms driving the accumulation of cellular waste and protein aggregates is crucial in biogerontology. Research explores the link between metabolic changes and aging, examining interventions like metformin. Researchers also focus on age-related neurodegenerative diseases, aiming to develop treatments and preventative measures.
• Biogerontology seeks to identify biomarkers of aging to monitor an individual's biological age. The study focuses on discovering the optimal combination of interventions, including diet, exercise, and medication, to extend both lifespan and healthspan. Ethical considerations of extending lifespan are an important topic within biogerontology.