Biologics

Biologics, also known as biological products or biopharmaceuticals, are medicinal products derived from biological sources, such as human, animal, or microorganism cells, through recombinant DNA technology and other advanced biotechnological methods. They are used to diagnose, prevent, or treat a wide range of diseases, often targeting specific molecules or pathways within the body. Unlike traditional pharmaceuticals, which are typically synthesized chemically, biologics are complex molecules, including proteins, antibodies, nucleic acids, and vaccines, making their manufacturing and regulatory processes intricate. These complex medications present unique manufacturing challenges and require specialized handling and storage to maintain their integrity and efficacy. They are used in areas such as cancer treatment, autoimmune disease management, and infectious disease prevention.

Biologics meaning with examples

• The oncologist prescribed a biologic to treat the patient's advanced melanoma, a targeted therapy designed to inhibit cancer cell growth. The patient underwent regular infusions, monitoring their response and any potential side effects. This biologic has shown significant improvement in the survival rate and quality of life.
• For years, Sarah struggled with rheumatoid arthritis, but a biologic revolutionized her treatment, managing inflammation and preventing joint damage. This treatment involves regular subcutaneous injections, allowing Sarah to reduce her reliance on oral medications. This improved her mobility and overall quality of life.
• The researchers are developing a new biologic vaccine to combat a specific strain of influenza, aiming to produce a more targeted and effective immune response. Clinical trials are underway to assess safety and efficacy before it can be approved for widespread use. This is vital for the global need for effective flu protection.
• Biologics, like those used to treat Crohn's disease, are often administered intravenously or through injections, allowing for direct delivery into the bloodstream. The drug specifically targets inflammation-causing proteins in the digestive tract, which reduces the severity of the symptoms and improves the patient's well-being.