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Cholestasis

Cholestasis is a condition where the flow of bile from the liver is slowed or blocked. This can lead to a buildup of bilirubin, bile acids, and other substances in the liver and bloodstream. The underlying cause can vary, ranging from gallstones and tumors to infections and drug-induced liver injury. Symptoms often include jaundice (yellowing of the skin and eyes), dark urine, pale stools, and itching. Treatment focuses on addressing the cause and managing symptoms.

Cholestasis meaning with examples

  • The patient's bloodwork revealed elevated bilirubin levels, indicating cholestasis, likely caused by a gallstone obstructing the bile duct.
  • Chronic cholestasis associated with primary biliary cholangitis can lead to severe liver damage if left untreated.
  • Prolonged use of certain medications may induce drug-induced cholestasis, necessitating a review of the patient's current prescriptions.
  • Early detection and treatment of cholestasis are crucial to prevent complications like liver cirrhosis and liver failure.
  • Infants can sometimes develop neonatal cholestasis, requiring specific diagnostic tests and management strategies.

Cholestasis Crossword Answers

7 Letters

ACHOLIA

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