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Derivatized

Derivatized refers to the process of chemically modifying a compound to create a derivative, which can enhance properties such as volatility, solubility, or detection capability. This term is commonly used in chemistry, particularly in the context of analytical methods and reactions to improve the identification and quantification of compounds.

Derivatized meaning with examples

  • In chromatography, compounds must often be derivatized to make them more amenable to separation; for instance, alcohols can be converted into silyl esters to improve their volatility during analysis.
  • The laboratory synthesized several derivatized analogs of the original compound to test for increased biological activity, making it easier to identify potential drug candidates.
  • In environmental studies, researchers derivatized samples of organic pollutants to facilitate their detection in complex matrices such as soil and water samples.
  • When studying complex mixtures, scientist will derivatize the components to improve their resolution in mass spectrometry, aiding in the accurate identification of trace substances.
  • While performing spectroscopy, the sample was derivatized to create a more stable product, thus allowing for a better resolution and identification of its molecular structure.

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