Describing the final, irreversible phase of a progressive disease or condition. It signifies a point where the body's ability to function adequately is severely compromised, often resulting in significant physical decline and a reduced life expectancy. The term is frequently used in medicine to describe the ultimate stages of illnesses such as kidney disease, heart failure, liver disease, and cancer, where therapeutic interventions become primarily focused on symptom management and palliative care, aiming to improve the patient's quality of life during this difficult period. This phase is characterized by limited treatment options and a focus on comfort and dignity.
End-stage meaning with examples
- The patient's chronic kidney disease progressed to end-stage, necessitating dialysis to filter waste products from the blood. Her kidney function had deteriorated significantly over several years, impacting her daily life with fatigue and swelling. Ultimately, her kidneys were no longer able to function properly on their own, requiring this life-sustaining treatment to manage her health.
- After years of struggling with heart failure, he reached the end-stage of the disease, making a heart transplant his only chance. His heart was severely damaged, and unable to pump enough blood. The doctors informed the family of their only option to have a chance at a new life, while accepting a difficult choice.
- Despite aggressive chemotherapy, the cancer had advanced to an end-stage, with the disease spreading to multiple organs. The doctors were no longer able to stop the cancer, their only hope was to provide comfort for the patient. The family were forced to make difficult choices, while focusing on comfort.
- The diagnosis of end-stage liver disease meant the patient's liver was failing, primarily due to years of alcohol abuse. The impact on their health was severe, with fluid retention and jaundice. The medical team prepared for a potential transplant to improve the patient's life.
- Following the progression of ALS, the patient was in the end-stage, having lost almost all muscular function and requiring mechanical ventilation to breathe. The patient's family were given the opportunity to be with them during this time. The hospice team focused on providing the best possible care and comfort for the patient.