Hypertrophic

Hypertrophic describes the enlargement or overgrowth of an organ or tissue due to an increase in the size of its cells. This often results from increased functional demand or hormonal stimulation. The term can apply to various biological structures, including muscles, the heart, or other organs. It indicates a state of physiological or pathological change where the affected tissue has expanded beyond its normal size, impacting its structure and, potentially, its function. Hypertrophy, the underlying process, is not necessarily inherently detrimental, though it can lead to adverse health outcomes if the excessive growth impairs normal operations. The context in which 'hypertrophic' is used often defines the degree to which it is beneficial or harmful.

Hypertrophic meaning with examples

• After intense weightlifting, the athlete's skeletal muscles exhibited a hypertrophic response, leading to significant increases in muscle mass and strength. This adaptive change allowed for increased power output during exercises, demonstrating the body's capacity to accommodate demands.
• The patient's heart showed hypertrophic changes due to prolonged hypertension. The thickened heart muscle, initially a compensatory mechanism, eventually strained the cardiovascular system, increasing the risk of heart failure over time and demonstrating maladaptation.
• In certain skin conditions, fibroblasts may undergo hypertrophic proliferation, forming thick, raised scars known as keloids, which may cause pain and limited movement and lead to severe aesthetic concerns.
• The use of certain anabolic steroids can result in a hypertrophic effect on muscle cells, promoting enhanced muscle growth and a significant increase in overall body size. However, side effects like organ dysfunction are possible.
• During pregnancy, the uterine muscles undergo hypertrophic expansion to accommodate the developing fetus. This physiological adaptation is crucial for carrying the pregnancy to term without issue.