In-molecule

An 'In-molecule' refers to the incorporation or presence of a specific molecule or molecular component within another, larger structure or system. It signifies the integration of a molecule into a more complex entity, often implying a functional role or contribution to the properties of the containing structure. This can apply to various scientific fields, including chemistry, biology, and materials science, where the inclusion of one molecule influences the behaviour or characteristics of the host molecule or system. The 'In-molecule' state highlights a relationship of containment and interaction, suggesting a non-isolated presence.

In-molecule meaning with examples

• In drug design, a therapeutic molecule is designed as an 'In-molecule' within a liposome, a microscopic sphere. The liposome encapsulates the drug, protecting it from degradation and facilitating its delivery to target cells, improving the drug's effectiveness and reducing side effects. This strategy transforms a free-floating drug into a controlled delivery system.
• In materials science, carbon nanotubes can have 'In-molecules' of organic polymers introduced during their formation. The polymer molecules, inside the nanotube, may enhance its structural integrity, electrical conductivity, or ability to interact with other substances. The 'In-molecule' interaction results in an improved composite material.
• In biochemistry, a coenzyme molecule, for instance, is considered an 'In-molecule' in its respective enzyme, playing a critical role in catalytic reactions. The coenzyme cannot function without the enzyme and modifies its activity. Without the coenzyme, the enzyme could be completely inactive and fail to perform its essential catalytic functions.
• In supramolecular chemistry, a guest molecule is an 'In-molecule' within a host molecule's cavity, such as a cyclodextrin. This inclusion complex is a highly specific interaction where the guest is trapped and may alter the host's properties and function. This is a key concept in sensing and recognition systems.