Keratolytic

A keratolytic is a substance or agent that causes the separation and shedding of the outer layer of the skin (the stratum corneum), which is composed of keratin. This action works by either dissolving the protein bonds that hold skin cells together or increasing the rate of skin cell turnover. Keratolytics are used to treat a variety of skin conditions characterized by excessive keratin buildup, such as warts, calluses, corns, and some types of psoriasis. Their use should be supervised by a medical professional.

Keratolytic meaning with examples

• Salicylic acid is a common keratolytic found in over-the-counter wart treatments. It works by softening and dissolving the keratin, allowing for the wart to be gradually removed through controlled peeling, and is effective with regular use. Consistent application helps to break down the thickened skin structure.
• A dermatologist prescribed a keratolytic cream containing urea for a patient suffering from severe dry skin and thick scaling on their feet. The cream's keratolytic properties helped to reduce the scaling and restore the skin's natural moisture balance, significantly improving comfort and appearance.
• For the treatment of stubborn calluses, a podiatrist might recommend a keratolytic patch to be applied directly to the affected area. This concentrates the active agent at the point of need, facilitating the breakdown of the hardened tissue and helping speed up the softening process.
• The doctor recommended a topical keratolytic to help manage psoriasis plaques. This medication helped loosen and remove the scales, allowing other treatments, such as steroid creams, to penetrate the skin more effectively and work as intended.