Neuroprotectant

A neuroprotectant is a substance or therapeutic intervention designed to safeguard neurons from damage, degeneration, or death. It works by mitigating or counteracting the pathological processes involved in neurological disorders, such as stroke, Alzheimer's disease, Parkinson's disease, and traumatic brain injury. Neuroprotectants may operate through various mechanisms, including reducing oxidative stress, inflammation, excitotoxicity, or promoting neuronal survival and regeneration. The ultimate goal is to slow or halt the progression of neurodegenerative diseases and improve patient outcomes.

Neuroprotectant meaning with examples

• Researchers are actively investigating the potential of specific antioxidants as neuroprotectants against the oxidative damage associated with Alzheimer's disease. Their aim is to find a substance that can slow the cognitive decline.
• After a stroke, administering a neuroprotectant could limit the size of the infarction and preserve surrounding brain tissue, leading to better functional recovery and reduced long-term disability for affected people.
• Clinical trials are underway to evaluate the efficacy of a novel neuroprotectant drug in delaying the onset or progression of Parkinson's disease by addressing the loss of dopamine-producing neurons.
• Following a traumatic brain injury, using neuroprotectants to reduce inflammation and prevent further cell damage can improve the chances of a full recovery and minimizing lasting neurological consequences in victims of accidents.