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Single-molecular

Relating to or involving a single molecule. It describes processes, reactions, or systems where the fundamental unit of interaction or observation is an individual molecule, rather than a collective of molecules. This level of focus allows for detailed study of molecular behavior, reaction kinetics, and interactions that would be obscured by bulk measurements. single-molecular investigations offer insights at the most fundamental level of chemistry, biology, and materials science.

Single-molecular meaning with examples

  • Single-molecular spectroscopy techniques allowed scientists to observe the conformational changes in a protein molecule in real-time. This gave us new insights into how these changes related to its function and how they interacted with other molecules. Studying molecules individually allowed for a level of detail and precision previously unattainable.
  • The design of single-molecular transistors is a major focus of nanoelectronics research, with the goal of creating extremely small and efficient electronic components. The precise control of single molecules and how they interact with the other molecules is critical for the function of the transistor in the circuitry.
  • Single-molecular imaging techniques such as fluorescence microscopy are used to track the movement and interactions of individual molecules within a living cell. Scientists observe this in their laboratory to further their understanding of cellular processes, like the cell's signal pathways and how they interact.
  • In drug discovery, single-molecular studies can identify the precise binding sites of a drug molecule to its target protein. This information can be used to design more effective and selective medications, and potentially predict the effects on other molecules if given the opportunity to interact with the target.
  • The study of single-molecular catalysis helps researchers understand the underlying mechanisms of enzyme activity. This information can inform the development of artificial catalysts that mimic the efficiency and selectivity of enzymes, possibly with an increased efficiency.

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