Ulceration

Ulceration refers to the formation or process of developing an ulcer, a break in the skin or mucous membrane with loss of surface tissue, inflammation, and often pus formation. This pathological process results from tissue destruction due to impaired blood supply, infection, chronic irritation, or underlying disease. The term encompasses the stages from initial injury to complete tissue breakdown, representing a significant disruption of normal bodily structure and function. The severity of ulceration varies greatly depending on the cause and depth of the affected tissues, ranging from superficial erosions to deep, penetrating lesions that can compromise underlying structures such as blood vessels and bone.

Ulceration meaning with examples

• The chronic pressure from his wheelchair resulted in severe ulceration on his sacrum, causing significant pain and requiring extensive wound care to prevent further tissue damage and infection.
• Poor hygiene and untreated diabetes contributed to the gradual ulceration of the patient's foot, highlighting the need for proactive health management to mitigate complications.
• A gastric ulcer, a common form of ulceration within the digestive tract, was identified during the endoscopy, leading to an aggressive treatment plan to prevent potential perforation.
• Radiation therapy, aimed to combat cancer, unfortunately led to oral ulceration, necessitating pain management and careful monitoring of the affected mucous membranes.
• Exposure to harsh chemicals resulted in severe skin ulceration on the worker's hands, necessitating immediate medical attention and changes to safety protocols.