Untranslocated

Referring to something that has not been moved from its original location, especially within a biological system. In the context of biology, 'untranslocated' often describes substances like nutrients, genetic material, or signals that have not been transported from their point of origin to another site within an organism or cell. This lack of movement can be due to various factors, including physical barriers, lack of transport mechanisms, or energy constraints. The term is crucial in understanding processes like nutrient distribution, genetic expression, and signal transduction pathways. It highlights a state of immobility or containment, playing a key role in the spatial regulation of biological functions.

Untranslocated meaning with examples

• The experiment revealed that the herbicide prevented sugar from becoming untranslocated, leading to the plant's death. The roots retained the sugar produced in the leaves. This lack of sugar transport was a key mechanism of action, disrupting essential processes required for plant life. The test revealed a distinct effect of the herbicide, as the sugar molecules could not reach the root.
• Researchers found that specific proteins remained untranslocated within the cell, preventing them from reaching the nucleus where they needed to perform their function. This restriction hampered gene expression and subsequent cellular processes. The untranslocated proteins were detected in the cytoplasm, unable to pass through the nuclear pore. This lack of movement impacted DNA function.
• In the study, the signaling molecules remained untranslocated across the cell membrane, inhibiting the initiation of downstream signaling pathways. As a result, the cells failed to respond effectively to external stimuli. This was identified by the researchers to the failure of the cells' response pathway. The receptors could not be activated, leading to an important consequence of a lack of reaction.
• A mutation in the transport protein resulted in an essential nutrient being untranslocated, causing a deficiency in the tissues that needed it. The lack of transport was a source of the cells’ troubles. The essential element became deficient, leading to impaired metabolic function. The nutrient did not reach its target site, which led to the cell failing.
• Genetic material was observed to be untranslocated within the virus particle, preventing it from interacting with the host cell's machinery. The key factor in the study was the blockage of the virus reproduction. The virus had a low rate of replication, which caused the virus to lose efficacy in the cells. The failure of the transfer was noted.