Zygotene is the third stage of prophase I in meiosis, the process of cell division in sexually reproducing organisms. This crucial stage, lasting from minutes to days depending on the species and the nature of the organism, follows leptotene and precedes pachytene. During zygotene, homologous chromosomes (pairs of chromosomes, one inherited from each parent) begin to pair up or synapse along their entire length. This pairing is facilitated by the synaptonemal complex, a protein structure that acts like a zipper, holding the homologous chromosomes tightly together. The initiation and completion of synapsis are essential for genetic recombination and proper chromosome segregation during meiosis. This detailed process of Zygotene ensures the correct number of chromosomes in the offspring. During this phase, the cells also synthesize an array of proteins to enable the process of chromosome pairing.
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