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Alkaloid-intolerant

Describing an individual or organism exhibiting adverse reactions or sensitivity to alkaloids. Alkaloids are a diverse group of naturally occurring organic compounds, primarily nitrogen-containing, often produced by plants and possessing physiological effects. Alkaloid-intolerance manifests through various symptoms, ranging from mild digestive discomfort to severe allergic reactions and potentially life-threatening consequences, depending on the specific alkaloid, its concentration, and the individual's susceptibility. This intolerance arises due to an inability to metabolize or effectively process these compounds, leading to a buildup within the body and subsequent toxic responses. Diagnosis often involves careful dietary history and sometimes allergy testing.

Alkaloid-intolerant meaning with examples

  • The doctor advised Sarah, who exhibited digestive upset after consuming chocolate (containing the alkaloid theobromine), to be cautious about consuming coffee and tea. She was, therefore, deemed alkaloid-intolerant. Avoiding these substances was critical to prevent further episodes and ensure her well-being.
  • Farm animals, especially certain livestock, are sometimes alkaloid-intolerant to particular plant species. A grazing sheep suffering from 'trembles' after ingesting certain weeds shows intolerance, and farmers must be mindful of poisonous plants within pasture areas to avoid animal illness.
  • Research studies explored the effect of diet on patient's migraine. Researchers found that a sub group of people with the condition are alkaloid-intolerant. Avoiding foods like aged cheeses, red wine (containing alkaloids) often significantly improved the frequency of migraine headaches.
  • After discovering the symptoms of nightshade, which contains alkaloids, the patient with muscle weakness and skin rashes was referred to a specialist. The specialist confirmed that a strong alkaloid-intolerant resulted from prolonged exposure to the plant.
  • Due to recurring stomach cramps after eating tomatoes, which contained alkaloids, the patient started on an elimination diet. Once the tomatoes were removed and the cramps stopped, a diagnosis was made: the patient was alkaloid-intolerant, and it was necessary to avoid those foods.

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