Oligomeric

Referring to a molecule or compound consisting of a relatively small number of repeating units (monomers). The term is often used in biochemistry, polymer chemistry, and materials science to describe substances that fall between monomers (single units) and polymers (long chains of many repeating units). oligomeric structures often exhibit properties that are distinct from both their monomeric and polymeric counterparts, influencing their reactivity, solubility, and physical characteristics. This term highlights the intermediate structural complexity of these molecules.

Oligomeric meaning with examples

• Researchers synthesized an oligomeric peptide to investigate its ability to cross the blood-brain barrier. Its shorter chain length, compared to longer proteins, proved advantageous for easier cellular uptake. These oligomeric structures are often modified with chemical groups to enhance their stability and targeting capabilities within the body.
• During protein folding, specific amino acid sequences can form stable oligomeric structures. These oligomeric forms might be dimers, trimers, or higher-order assemblies that dictate the protein's function. Understanding the oligomeric state is critical for designing drugs that interact with these proteins.
• In the development of novel plastics, researchers explored the use of oligomeric precursors that could then polymerize under specific conditions. These oligomeric forms offered benefits over monomeric forms such as improved processability and reduced volatility.
• The study investigated the effect of an oligomeric compound on bacterial cell wall synthesis. The oligomeric structure of the compound allows it to bind to several targets in the bacterial cell. This multivalent binding is often important for effective inhibition of bacterial activity.
• A new class of oligomeric catalysts was designed to enhance the efficiency of a chemical reaction. The oligomeric catalysts showed improved activity and selectivity, compared to their monomeric counterparts, due to their unique structural arrangement and interaction with the reactants. The oligomeric structure enhances the catalytic activity.